The number of new mpox cases reported in Chicago last week was the lowest weekly total reported to CDPH since mid-August and marks four consecutive weeks of a decline in new cases. In mid-October, there were seven new mpox cases reported in Chicago, down from 13 the previous week, 14 the week before that, and 15 at the end of September. This trend is encouraging, but CDPH still urges anyone who may be in a vulnerable group to take necessary care to avoid mpox, including vaccination. From June 1 – Oct. 18, 2025, 141 cases of mpox have been reported to CDPH.  CDPH is co-sponsoring several mpox vaccination events throughout November, including:  

• Sunday, November 9 (1-4 p.m.) and Monday, November 10 (6-9 p.m.): Touche Bar, 6412 N. Clark St. 

• Wednesdays, November 5, 12, 19, and 26 (5:30 – 7:30 p.m.): Steamworks Baths, 3246 N. Halsted St.

Vaccination is especially encouraged for sexually active gay, bisexual, and same-gender-loving men, who have been most affected by this mpox outbreak. The mpox vaccine is also available at CDPH’s Sexual Health Clinics in Lakeview, Roseland, and Austin.